Circumstances of dengue fever, often known as “break-bone” fever1 on account of excessive joint ache being one in all its hallmark signs, are hovering worldwide, with many nations reporting larger than traditional numbers. Whereas a majority of the circumstances are seen in tropical and subtropical areas like South Asia, Africa and South America,2 U.S. well being officers have lately sounded the alarm a couple of rise of circumstances in a number of states.
In June 2024, the U.S. Facilities for Illness Management and Prevention (CDC) issued an alert relating to the growing dengue incidents within the Americas.
As of the most recent epidemiological replace from the Pan American Well being Group (PAHO),3 a record-breaking 9,852,482 suspected dengue circumstances have been recorded from January to June 2024 — that’s twice as many because the reported circumstances (4.6 million) in 2023.4 “This represents a rise of 231% in comparison with the identical interval in 2023 and 420% in comparison with the typical of the final 5 years,” PAHO studies.5
Two Florida Counties Report Growing Dengue Circumstances
With its humid, subtropical climate all 12 months spherical — the right breeding situations for mosquitoes — Florida is likely one of the states being carefully monitored for a possible dengue outbreak. In keeping with the CDC, 197 dengue fever circumstances have been reported within the state. Whereas the bulk are travel-related (that means contaminated locals have lately visited different areas the place dengue is endemic), there are additionally studies of regionally transmitted circumstances.6
One of the crucial current regionally acquired circumstances was in Hillsborough County, reported by the Florida Division of Well being on June 24.7 In the meantime, Miami-Dade County has reported six regionally acquired circumstances this 12 months.8 Though considerably decrease than final 12 months’s numbers — Miami-Dade had 173 regionally acquired circumstances in 2023 — it’s nonetheless a trigger for concern.
Different states like Hawaii, Texas, California and Arizona have additionally beforehand reported small native outbreaks of dengue fever9 in accordance with the CDC, cautioning residents to be notably vigilant.
“Dengue stays much less widespread within the continental United States, however within the 50 states to this point this 12 months there have been thrice extra circumstances than on the similar level final 12 months. Most have been infections that vacationers obtained overseas, and officers be aware there is no such thing as a proof of a present outbreak. However additionally they warn that native mosquitoes pose a risk,” CBS Information studies.10
Primary Details About Dengue Fever
The dengue virus is a single positive-stranded RNA virus that belongs to the Flaviviridae household and is transmitted to people by the Aedes mosquito species, notably Aedes albopictus, Aedes polynesiensis and Aedes scutellaris.11 These small, black mosquitoes will be recognized by the white stripes on their again and legs; the females lay their eggs in standing water. In keeping with the Washington Publish:12
“A single bottle cap stuffed with rainwater can maintain greater than 100 [mosquito] eggs, stated Sadie Ryan, a medical geographer on the College of Florida who makes a speciality of insect-borne ailments.
‘They’re tenacious, they’re pernicious,’ Ryan stated. ‘Actually, they’re simply good at being all over the place.’ They behave like tiny vampires at a human buffet, flitting from individual to individual, doubtlessly spreading illness with every chew.”
The Aedes mosquito can unfold 4 sorts of dengue viruses, specifically DENV-1, -2, -3 and -4, that are distinct however carefully associated. The CDC notes that about 1 in 4 individuals who turn out to be contaminated with the virus will get sick with dengue fever; the bulk stay asymptomatic. When symptomatic, dengue fever may very well be both delicate or extreme.13
Dengue’s incubation interval — from the time between publicity to when the signs begin to manifest — is usually between 4 and 7 days, though in some circumstances it may take so long as 14 days.14 Signs embody:
A excessive fever round 104 levels F or (40 levels C) |
Extreme headache |
Ache behind the eyes |
Joint and muscle ache |
Nausea and vomiting |
Swollen glands |
Rash |
Kids with dengue fever can also expertise widespread chilly and gastroenteritis-like signs.15 In uncommon situations — about 1 in 20 sufferers — dengue fever can develop right into a extreme sickness. Indicators of extreme dengue often seem one to 2 days after the fever has subsided, and if not handled, might result in shock, inside bleeding and even dying.16
You probably have been recognized with dengue fever and expertise the signs beneath, it’s essential to hunt fast therapy instantly:17,18
Extreme stomach ache or tenderness |
Vomiting (at the least thrice in 24 hours) |
Bleeding from the nostril or gums |
Feeling extraordinarily drained or stressed |
Vomiting blood or blood within the stool |
Speedy respiratory |
Pale and chilly pores and skin |
Elevated thirst |
Puerto Rico Has Declared a Dengue Epidemic
Though extreme dengue fever might happen throughout major an infection, most situations happen throughout secondary an infection — that is when you could have been beforehand contaminated with one DENV pressure after which re-infected with one other pressure. CBS explains:19
“When somebody is first contaminated, their physique builds antibodies towards that kind for all times. In the event that they get contaminated with one other kind of dengue, the antibodies from the primary an infection might fail to neutralize the second kind —and really will help the virus enter immune cells and replicate.”
It is a rising concern in Puerto Rico, which has been extensively uncovered to DENV-1 for the final 20 years. In keeping with Dr. Gabriela Paz-Bailey, the Puerto Rico-based chief of the CDC’s dengue department, “We’re presently seeing will increase within the circumstances on account of dengue 2 and dengue 3, for which the inhabitants has little or no immunity.”20
Puerto Rico declared a dengue epidemic in March 2024, with 549 circumstances reported and greater than 340 hospitalized.21 Many of the circumstances have been seen within the capital of San Juan. In Could, the island reported its first dengue-caused dying for the 12 months.22 By June, the quantity soared to a whopping 1,498 circumstances,23 which is larger than the general dengue circumstances (1,293) from all of 2023.24
Nevertheless it isn’t simply Puerto Rico and the Americas which can be experiencing this surge. Worldwide, dengue circumstances have considerably elevated within the final 5 years, in accordance with the World Well being Group (WHO). Presently, 90 nations have identified lively transmission of this illness.25
There’s No Typical Remedy for Dengue
Dengue fever is never deadly, however for those who do fall unwell due to this an infection, it’s essential to handle your signs and keep hydrated to assist your self recuperate. There isn’t any identified therapy for dengue; delicate circumstances will be managed at dwelling with ache medicine and fluids. In extreme circumstances, hospitalization could also be vital to make sure correct restoration.
The dengue virus messes along with your bone marrow cells, which inhibits platelet manufacturing.26 This results in thrombocytopenia, or a speedy decline in platelet depend. Because of this, platelet infusions are sometimes suggested with typical therapy.
Nonetheless, there’s rising analysis27,28,29 stating that transfusions to extend platelet depend is questionable, and will trigger additional unfavourable results. One examine, printed in 2022 within the journal Case Stories in Hematology,30 notes:
“Thrombocytopenia is a quite common scientific manifestation in dengue. The platelet depend might drop very abruptly, however more often than not it follows its personal scientific course and ought to be managed conservatively … It is rather essential for clinicians to know that platelet transfusions don’t have any profit in treating thrombocytopenia in dengue and ought to be averted as they could trigger vital uncomfortable side effects.”
Three years in the past, New Delhi, India, skilled a dengue fever outbreak, which overwhelmed their native hospitals and led to a excessive demand in platelets. Nonetheless, whereas sufferers manifesting extreme signs like very low platelet depend, inside bleeding or rashes might profit from transfusions, the docs have been usually towards preventive transfusions.31
In a Instances of India article,32 Dr. Jyoti Kotwal, chairperson of the division of hematology at Sir Ganga Ram Hospital, commented:
“Transfusion runs the danger of transmitted infections. Platelet transfusion shouldn’t be overprescribed. In our hospital, we conduct immature platelet fraction checks earlier than deciding whether or not a affected person wants transfusion or not. It measures younger platelet depend as an alternative of absolute depend, which is a extra dependable indicator of severity.”
Dr. Rommel Tickoo, director of inside medication at Max Saket Hospital, echoed this sentiment, and stated majority of sufferers can profit from correct hydration and supportive remedy as an alternative, in addition to getting examined on time.
“We see sufferers who maintain ready at dwelling with excessive fever for 5 to 6 days and rush to hospital with extreme signs. … Get the dengue take a look at carried out if fever and different signs persist for 2 days or extra for well timed prognosis and therapy,” he suggested.33
These Pure Cures Could Assist With Dengue Restoration
Whereas there aren’t any drugs that may remedy dengue fever, you possibly can flip to sure meals, natural treatments and dietary supplements to assist naturally strengthen your immune system, improve platelet depend and handle signs to assist facilitate the therapeutic course of.
In a single 2023 examine,34 for instance, scientists discovered that 4 sorts of carbohydrate-binding brokers (CBAs) will help stop the dengue virus from attaching to host cells, inhibiting the an infection’s progress.
Amaryllis (Hippeastrum hybrid), Bovine lactoferrin (a protein present in cow’s milk), stinging nettle (Urtica dioica) and customary snowdrop (Galanthus nivalis) have been discovered to intervene with the virus’s capacity to connect to wholesome cells. This helps inhibit an infection within the early levels:
“It was proven that the binding of HHA to the DENV-2 E protein blocked the interactions between DENV-2 and DC-SIGN, subsequently interfering with DENV-2 attachment to the host cells.
This indicated that these CBAs acted throughout an early stage of DENV an infection by stopping viral attachment to DC-SIGN receptors on host cells,” the researchers famous.35
As well as, sure natural treatments have antiviral properties that will assist with dengue fever restoration. These embody:
1. Carica papaya (Caricaceae) — A 2024 examine printed within the Asian Plant Analysis Journal36 says that leaf extracts of this unique plant, native to Sri Lanka, can “neutralize plasma with the dengue virus, scale back platelet aggregation, and improve the manufacturing of the enzyme ALOX12, which promotes platelet manufacturing” in dengue sufferers.
An earlier examine, printed within the Sri Lankan Journal of Infectious Ailments in 2021,37 discovered that C. papaya extracts might assist inhibit DENV-1 infections, suggesting “the potential of C. papaya leaf extract for future growth of antiviral medication towards DENV-1.”
2. Euphorbia hirta (Euphorbiaceae) — Also referred to as “bronchial asthma plant,” this branched herb solely grows as much as 70 centimeters excessive however reveals promising potential with its antiviral properties. One evaluation printed in 202238 notes that scientific investigations of E. hirta amongst dengue sufferers ages 30 to 35 years outdated discovered that supplementing with this herb helped scale back flu-like signs by roughly 70%. In keeping with the examine authors:39
“The in vitro evaluation of the ethanolic extract of the plant confirmed exceptional inhibition of plaque formation as much as 85% and 34.7% towards DENV-1 and DENV-2, respectively.”
Within the Philippines, the place extra dengue circumstances are being reported this 12 months in comparison with 2023,40 a water decoction made with E. hirta leaves is used to assist recuperate from this situation.41
3. Velvetleaf (Cissampelos pareira) — Native to Sri Lanka, India and the Amazon forest, velvetleaf is a flowering plant that belongs to the Menispermaceae household. A examine42 highlights it as one of many botanicals which have proven promise in inhibiting DENV replication, noting that:
“Nearly all elements … like aerial elements, roots, and stem barks in addition to the entire vegetation present protecting results towards DENV, which aren’t restricted to DENV-2 or DENV-1 solely, but additionally towards kind 3 (DENV-3) and sort 4 (DENV-4).”
4. Elderberry (Sambucus nigra L.) — Belonging to the household Adoxaceae, elderberry is wealthy in flavonoids, that are chargeable for its antiviral exercise. Except for the extract, elder flowers and leaves have been discovered to have antiviral results towards the DENV-2 pressure, at concentrations of 400 micrograms/milliliter (ug/ml).43
5. Garlic (Allium sativum) — Garlic has been extensively praised for its antibacterial, antioxidant, anticarcinogenic and different therapeutic properties. One examine notes that the organosulfur compounds on this herb, notably diallyl disulfide (DADS), diallyl sulfide (DAS) and alliin, might considerably inhibit the inflammatory cytokines in DENV-2 an infection.44
Diet Issues — Enhance Your Consumption of These Vitamins
Getting sufficient relaxation, staying hydrated and consuming a nutritious diet are all important methods for those who’re recovering from a viral illness like dengue fever. Throughout this time, it’s notably essential to get ample quantities of wholesome vitamins, as some might notably assist pace up the therapeutic course of.
A 2021 literature overview printed within the American Journal of Tropical Drugs and Hygiene45 highlights research from a number of nations on how supplementing with sure micronutrients might “provide hypothetical advantages to dengue sufferers through quite a few potential mechanisms, together with modulation of the host immune response.” Among the vitamins talked about embody:
- Vitamin C — Indian researchers46 discovered that sufferers who got supplemental vitamin C not solely had a shorter hospital keep, but additionally had larger platelet counts than those that didn’t take the complement.
- Vitamin D — A examine from Pakistan47 divided dengue sufferers into two teams; solely these within the first group acquired vitamin D dietary supplements. The researchers discovered that Ø…those that didn’t obtain the complement have been extra more likely to develop dengue hemorrhagic fever.
- Vitamin E — Researchers from Sri Lanka48 famous that dengue sufferers who acquired vitamin E dietary supplements confirmed “enhancements in varied scientific and hematological parameters, together with considerably larger subsequent platelet counts amongst sufferers admitted for thrombocytopenia.”
- Zinc — A examine49 carried out in Thailand discovered that supplementing with zinc led to a shorter length of hospitalization amongst kids contaminated with dengue.
For those who eat a wholesome, well-balanced weight-reduction plan loaded with complete meals together with vegatables and fruits, you’ll don’t have any scarcity of those vitamins. For instance, kiwi, dragon fruit and papaya are wealthy in nutritional vitamins A, C, E and potassium, all of which can assist promote immunity and improve your platelet depend naturally.50 As for vitamin D, the easiest way to spice up your ranges is to get common solar publicity as near photo voltaic midday as potential.
Prevention Is Nonetheless the Finest Course of Motion
Summer season is the most effective season to spend time in nature and beneath the solar, however the concern of being bitten by disease-ridden mosquitoes could make you hesitate. With the intention to maintain you from changing into a mosquito magnet throughout this season, I like to recommend taking these preventive measures, so you possibly can spend time outdoors with none worries:
Put on lengthy sleeves and pants if you already know you’ll be open air in a mosquito-prone space. |
Use pure insect repellants (not artificial chemical variations), like cinnamon leaf oil, citronella important oil or catnip oil, if vital. |
Use a home fan in your yard to maintain mosquitoes away when you’re open air. |
Strategic planting of marigolds, which mosquitoes are likely to avoid. |
Drain standing water, together with pet bowls, gutters, rubbish and recycling bins, spare tires, chicken baths and kids’s toys, as that is the place mosquitoes breed. |
Set up a bat home, as mosquitoes are one in all their favourite meals. |